Micky van de Ven Brace Halts Everton's Run at New Stadium
Micky van de Ven emerged as the initial defender to score twice in a English top-flight match for Tottenham since Jan Vertonghen in March 2013.
Match summary
The Spurs defender heads into the net two times in first half
The home side's Jake O'Brien has goal disallowed after VAR review
Pape Matar Sarr nets final goal in 89th minute
The defeat is the Merseyside club's initial at Hill Dickinson Stadium
Micky van de Ven found the net twice as Tottenham prolonged their unbeaten run on the road in the top division and delivered the Toffees their initial loss at their new home.
Everton were undefeated in their five previous fixtures at their new ground at the dockside location, having departed their historic home behind after more than a century at the end of the previous campaign.
But Tottenham's leader Van de Ven pounced on two occasions from corners in the opening 45 minutes to place their strong form at jeopardy, and they were failed to turn it around before the midfielder - set up by former Toffees attacker Richarlison - headed home a third to put the game to bed.
Jake O'Brien thought he had levelled the tally five minutes after Van de Ven's opener, directing a bullet header past the Spurs keeper from an set-piece.
Beto, in the meantime, failed to convert a handful of chances, while Vicario made a succession of fine saves to guarantee the London club went five away games unbeaten in the Premier League.
But the video assistant referee intervened, instructing the match official to review the score on the pitchside monitor and the official ruled that the winger and the attacker were in an illegal position and had impeded with the Spurs keeper.
This victory moves the manager's team up to third in the Premier League, a handful of points off local foes and table-toppers Arsenal.
The Merseyside club stay in 14th position and are six points ahead of the drop zone.
Spurs breakdown: Van de Ven fulfils role at both ends of pitch
Following a uninspiring midweek display in the European competition against the French side, where they mustered a only two shots on target, the manager opted for Randal Kolo Muani in attack instead of former Toffees player Richarlison.
The summer signing was unable to influence the game before being substituted for Richarlison after 60 minutes on the field, but it emerged he proved unnecessary in the final outcome.
Defender the Dutchman converted into an attacking force to be feared.
Tottenham's opening strike came from a well-worked corner routine, with Rodrigo Bentancur directing the ball back across the six-yard box for an free Van de Ven to head home.
And the captain - filling in as skipper in the Argentine's absence - notched his next goal in added time as he outjumped Jordan Pickford to nod in.
Van de Ven was just as impressive in defence, combining well with Kevin Danso as the duo handled superbly with the 34 crosses sent their way by Everton.
Everton analysis: Toffees lacking striker's instinct
The club's new home had been a fortress, but it seems the novelty may have worn off slightly and fans flocked to the gates after the midfielder's third for Tottenham.
The break in the team's unbeaten home run won't be a major worry for David Moyes, but their attacking woes are.
Beto and the other striker - the Everton's two recognised strikers - had netted just a single goal combined before Sunday's outing.
And they were failed to add to that poor record on a damp and dreary evening on Merseyside.
The striker's performance was epitomized when he chose to overhead kick a clear chance from close range, even with having room and time to readjust for a more conventional shot that would have challenged Vicario.
Barry, too, was unable to influence the game after coming on for the starter in the second half.
It wasn't for a shortage of opportunity. The majority of the home side's offensive moves came through Grealish and Ndiaye, who tirelessly delivered dangerous balls into the Spurs box.
What next for both teams?
The Toffees: Moyes' men head to the Stadium of Light in the Premier League on early November at 20:00 GMT.
Spurs: The London club go to Newcastle's ground on late October for their fourth-round Carabao Cup match against the Magpies.